When consumed, CBD can produce two distinct effects. The first is felt when taking a small amount and the second is experienced after a more potent serving.
This two-part characteristic is known as 'biphasic' and means that with careful application CBD can prove to be more useful than supplements with less varied effects.
A biphasic effect is when one substance acts in two different ways as the concentration increases. Alcohol is a great example of a substance that is Biphasic. When you drink a small amount of alcohol it gives an uplifting and stimulating effect. However, if you drink more and it passes a level of 0.05% in your bloodstream, it becomes a depressant and can make you subdued and tired.
There is growing evidence from scientific studies and user reports that CBD produces a biphasic effect. Some studies have reported different effects at different amounts. That research does not establish a universal daytime/evening rule for retail CBD use.
For a long time, it has been acknowledged that the amount of CBD used is critical to the research. In 2008, Antonio Zuardi, Professor of the School of Medicine at the University of Sao Paulo, was aware that the actions of CBD could be plotted as a bell curve, becoming more effective when specific amounts were in the bloodstream. “It is important to highlight that…the [amount] is a pivotal factor in CBD research.”
This effect has become a crucial factor for consumers, and manufacturers even include references to it in product directions.
While studies often use a standard amount for all participants, the effect of CBD depends on several factors that are unique to you. They include body mass, tolerance and chemical makeup.
Not noticing an effect does not by itself mean you should increase your CBD intake. Check the amount in each serving and the current FSA advice before changing how much you use.
Recording what you use can help you keep track of the CBD content across products. It is not a reason to keep increasing the amount.
The Food Standards Agency advises healthy adults to limit their total CBD intake from food to 10 mg a day as a precaution.
CBD’s effects can change with the amount used, and a larger serving does not necessarily produce a stronger effect.
Fact-checked by Dr Marios Kyriazis.
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Tom Russell
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Tom Russell writes extensively about CBD oil and other groundbreaking food supplements. He and his wife share their home with two daughters and a lifetime’s collection of books.